Motif ID: STAT5{A,B}.p2

Z-value: 1.444


Transcription factors associated with STAT5{A,B}.p2:

Gene SymbolEntrez IDGene Name
STAT5A 6776 signal transducer and activator of transcription 5A
STAT5B 6777 signal transducer and activator of transcription 5B

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
STAT5Bchr17_-_40428391-0.472.3e-01Click!
STAT5Achr17_+_40439564-0.423.1e-01Click!


Activity profile for motif STAT5{A,B}.p2.

activity profile for motif STAT5{A,B}.p2


Sorted Z-values histogram for motif STAT5{A,B}.p2

Sorted Z-values for motif STAT5{A,B}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT5{A,B}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_44860798 1.701 NM_001083335
NM_013380
 ZFP112

zinc finger protein 112 homolog (mouse)

chr5_+_178450775 1.507 NM_001136116
 ZNF879
zinc finger protein 879
chr19_+_35168558 1.452 NM_001012320
NM_018443
 ZNF302

zinc finger protein 302

chr19_+_44617510 1.313 NM_013362
 ZNF225
zinc finger protein 225
chr19_-_44405934 1.105 LOC100505715
uncharacterized LOC100505715
chr19_-_44809126 1.091 NM_004234
 ZNF235
zinc finger protein 235
chr19_+_44764032 1.077 NM_001207005
NM_181756
 ZNF233

zinc finger protein 233

chr5_-_111093251 1.067 NM_001142479
NM_001142480
NM_001142478
 C5orf13


chromosome 5 open reading frame 13


chr9_-_115774471 0.943 NM_001101338
 ZNF883
zinc finger protein 883
chr11_+_65268313 0.942 MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr19_+_44529493 0.899 NM_001129996
NM_013360
 ZNF284
ZNF222

zinc finger protein 284
zinc finger protein 222

chr19_-_37958338 0.871 NM_152484
 ZNF569
zinc finger protein 569
chr19_+_35225095 0.853 ZNF181
zinc finger protein 181
chr19_+_44669214 0.845 NM_001146220
NM_001032373
NM_001032374
NM_015919
NM_001032372
 ZNF226




zinc finger protein 226




chr6_-_27440459 0.802 NM_007149
 ZNF184
zinc finger protein 184
chr19_+_44556163 0.784 NM_013361
 ZNF223
zinc finger protein 223
chr19_+_44488331 0.770 NM_003445
NM_198089
 ZNF155

zinc finger protein 155

chr19_-_58090071 0.720 NM_017879
 ZNF416
zinc finger protein 416
chr20_-_18477811 0.713 NM_006606
 RBBP9
retinoblastoma binding protein 9
chr11_-_82996898 0.712 CCDC90B
coiled-coil domain containing 90B

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
2.38 4.15e-11 GO:0006355 regulation of transcription, DNA-dependent
2.29 3.32e-10 GO:0051252 regulation of RNA metabolic process
2.28 6.31e-11 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.25 9.97e-11 GO:0010556 regulation of macromolecule biosynthetic process
2.18 5.41e-10 GO:0010468 regulation of gene expression
2.16 2.18e-10 GO:0009889 regulation of biosynthetic process
2.16 3.12e-10 GO:0031326 regulation of cellular biosynthetic process
2.07 4.65e-09 GO:0051171 regulation of nitrogen compound metabolic process
2.07 1.58e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.89 4.12e-08 GO:0060255 regulation of macromolecule metabolic process
1.81 3.53e-07 GO:0031323 regulation of cellular metabolic process
1.81 3.66e-07 GO:0080090 regulation of primary metabolic process
1.74 8.03e-07 GO:0019222 regulation of metabolic process
1.28 3.39e-02 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.61 3.10e-09 GO:0005634 nucleus
1.40 1.43e-09 GO:0043231 intracellular membrane-bounded organelle
1.40 1.62e-09 GO:0043227 membrane-bounded organelle
1.36 1.68e-09 GO:0043229 intracellular organelle
1.35 2.10e-09 GO:0043226 organelle
1.24 1.70e-06 GO:0044424 intracellular part
1.23 4.26e-06 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
2.58 9.14e-15 GO:0008270 zinc ion binding
2.37 2.45e-13 GO:0046914 transition metal ion binding
2.27 1.75e-11 GO:0003677 DNA binding
1.91 1.39e-09 GO:0003676 nucleic acid binding
1.69 6.51e-07 GO:0046872 metal ion binding
1.67 1.24e-06 GO:0043169 cation binding
1.67 1.43e-06 GO:0043167 ion binding